Classifying this myriad of conditions — from arthritis to zoster pain — that we now understand to be instigated and advanced by this culprit biomarker, is critical in advancing the application of Gal-3 as both a prognostic indicator and key therapeutic target.

In the US, the researched form of MCP is patented for structure-function health claims related to cellular, cardiovascular and immune health, as well as inflammation, fibrosis and toxic metal body burden. Galectin-3 is a carbohydrate-binding protein made in the body anda key cancer marker. It is known to be involved in cancer parthenogenesis. It is also atherapeutic target for drugs and has been extensively researched for its role in promoting cancer and chronic disease. PectaSol-C Modified Citrus Pectin, Potassium, Sodium, Dietary Fiber, Vegetable capsule (natural vegetable cellulose, water), stearic acid, magnesium stearate, microcrystalline cellulose, silicon dioxide. A randomized controlled trial involving 87 patients with IBS and diarrhea symptoms showed that those who took daily pectin had significantly fewer symptoms, more formed stools, and better quality of life than those who took placebo. In 2018, for example, clinical results from an ongoing multicentre trial on this form of MCP in biochemically relapsed prostate cancer were presented at the American Society for Clinical Oncology Genitourinary Conference. Reported in the Journal of Clinical Oncology, the study — “Effects of Pectasol-C Modified Citrus Pectin Treatment on PSA Dynamics in Non-Metastatic Biochemically Relapsed Prostate Cancer Patients” — demonstrated the ability of the only researched form of MCP to significantly slow PSA doubling time and halt disease progression in the majority of subjects. 1 What is galectin-3 (Gal-3)?

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In May 2011, data from the Prevention of REnal and Vascular ENd-stage Disease (PREVEND) study, a 10-year all-cause mortality investigation involving close to 8000 people, demonstrated that elevated serum Gal-3 increased all-cause mortality three-fold in the general population. 7 Another compelling large-scale study showed lower levels of Gal-3 in centenarians compared with those in their sixties and seventies who didn’t live as long. 8

A number of scientific studies show that MCP can work synergistically with certain chemotherapy agents such as doxorubicin and paclitaxel . Extracellular Gal-3 acts as an adhesion surface protein, forming lattices with itself, binding glycoproteins and glycolipid membrane receptors and creating a gel-like biofilm that anchors other procancerous growth factors and inflammatory compounds within the extracellular matrix. PectaSol® Metal Detox has been clinically studied to support safe heavy metal toxin and radioactive particle removal from the body, and is formulated to provide additional support to prevent toxin reabsorption and redistribution through the gut wall.* PectaSol® Metal Detox exerts a dual action in the body. Algimate® Modified Alginate Complex remains in the digestive tract where it works to bind and eliminate heavy metals and radioactive particles to be eliminated through the stools. PectaSol-C® MCP is absorbed into the circulation from the intestine and works systemically, binding heavy metals and environmental pollutants in the circulation for safe elimination through the urinary system.*PectaSol-C Modified Citrus Pectin in a naturally extracted from the pith of citrus fruit peels and enzymatically modified to provide you with a highly pure, absorbable, and unique product. Brand D. Keizman, et al., Effect of Pectasol-C Modified Citrus Pectin (P-MCP) Treatment (tx) on PSA Dynamics in Non-Metastatic Biochemically Relapsed Prostate Cancer (BRPC) Patients (pts): Results of a Prospective Phase II Study,” J. Clin. Oncol. 36(6), 14 (2018).