Kossoff EH, Rho JM. Ketogenic diets: evidence for short- and long-term efficacy. Neurotherapeutics. 2009 Apr;6(2):406–414. doi: 10.1016/j.nurt.2009.01.005 PMID 19332337. This will give us an idea of how much the minimum amount of calories your body will burn in a day. Our keto calculator uses this to calculate your Basal Metabolic Rate (BMR). We use this number, along with your body fat percentage, to estimate how many calories you’ll need for your goals. HOW MUCH OF MY PLATE SHOULD BE FAT?Healthy fats make up around 50% of your plate but 75-80% of total calories, as fat has twice as many calories per gram compared to carbs and protein. Bergqvist AGC. Indications and Contraindications of the Ketogenic diet. In: Stafstrom CE, Rho JM, editors. Epilepsy and the ketogenic diet. Totowa: Humana Press; 2004. pp. 53–61. ISBN 1588292959.

It can seem complicated, but it’s honestly not! It’s just a ratio of protein. If you are 100 lbs. of muscle and want to gain muscle (1.0g protein), you eat 100g protein.Henderson CB, Filloux FM, Alder SC, Lyon JL, Caplin DA. Efficacy of the ketogenic diet as a treatment option for epilepsy: meta-analysis. J Child Neurol. 2006 Mar;21(3):193–198. doi: 10.2310/7010.2006.00044. PMID 16901419 In this article, kcal stands for calories as a unit of measure (4.1868kJ), and calories stands for "energy" from food. Römer M, et al. The use of ketogenic diets in cancer patients: a systematic review. Clin Exp Med. 2021 Nov;21(4):501–536. doi: 10.1007/s10238-021-00710-2. PMC 8505380 PMID 33813635 Protein intake is imperative when it comes to keto. Too much and you can lower your ketone levels, too little and you can lose excess muscle. You want to be in the sweet spot. Anticonvulsants suppress epileptic seizures, but they neither cure nor prevent the development of seizure susceptibility. The development of epilepsy (epileptogenesis) is a process that is poorly understood. A few anticonvulsants ( valproate, levetiracetam and benzodiazepines) have shown antiepileptogenic properties in animal models of epileptogenesis. However, no anticonvulsant has ever achieved this in a clinical trial in humans. The ketogenic diet has been found to have antiepileptogenic properties in rats. [59] Other medical applications

a b c d e f g h i Freeman JM, Kossoff EH, Hartman AL. The ketogenic diet: one decade later. Pediatrics. 2007 Mar;119(3):535–543. doi: 10.1542/peds.2006-2447. PMID 17332207 A typical diet plan allows you to lose 0.5-1 kg (1-2 lbs) per week. Faster weight loss might be dangerous for your health, while a slower pace requires a lot of patience. Naturally, you don't have to be losing weight on the ketogenic diet; a lot of people decide to start this diet because of other health benefits (you can find them in the section health benefits of the keto diet). a b Scottish Intercollegiate Guidelines Network. Guideline 81, Diagnosis and management of epilepsies in children and young people. A national clinical guideline (PDF). Edinburgh: Royal College of Physicians; 2005. ISBN 1899893245. The ketogenic diet reduces seizure frequency by more than 50% in half of the patients who try it and by more than 90% in a third of patients. [18] Three-quarters of children who respond do so within two weeks, though experts recommend a trial of at least three months before assuming it has been ineffective. [19] Children with refractory epilepsy are more likely to benefit from the ketogenic diet than from trying another anticonvulsant drug. [1] Adolescents and adults may also benefit from the diet, though compliance with oral diet (vs tube fed) remains a problem. [20] Trial design Once you know the recommended calorie intake for maintaining your current weight, you can modify it to achieve the desired results. As a first step, decide on your target weight – it can be lower or higher than your current one. Then, choose how fast you want to lose or gain weight.I’m the first to agree that the keto diet can seem overwhelming at times. Apart from turning your diet upside down, there also seems to be lots of rules that can trip you up. Following a strict macro-nutrient profile just adds to the confusion, especially when you’re starting out. There are some variations in the types of fiber and sugar alcohols that may not make this 100% accurate. While the net carb calculation isn't perfect, it's currently the best way to get an idea of how many digestible carbs you're eating. Why Count Net Carbs?

By using our keto calculator, you will find out how much of each macronutrient (i.e., fat, protein, and carbs) you need to eat so that you can: The brain is composed of a network of neurons that transmit signals by propagating nerve impulses. The propagation of this impulse from one neuron to another is typically controlled by neurotransmitters, though there are also electrical pathways between some neurons. Neurotransmitters can inhibit impulse firing (primarily done by γ-aminobutyric acid, or GABA) or they can excite the neuron into firing (primarily done by glutamate). A neuron that releases inhibitory neurotransmitters from its terminals is called an inhibitory neuron, while one that releases excitatory neurotransmitters is an excitatory neuron. When the normal balance between inhibition and excitation is significantly disrupted in all or part of the brain, a seizure can occur. The GABA system is an important target for anticonvulsant drugs, since seizures may be discouraged by increasing GABA synthesis, decreasing its breakdown, or enhancing its effect on neurons. [7] Liu H, Yang Y, Wang Y, Tang H, Zhang F, Zhang Y, Zhao Y. Ketogenic diet for treatment of intractable epilepsy in adults: A meta-analysis of observational studies. Epilepsia Open. 2018 Feb 19;3(1):9–17. doi: 10.1002/epi4.12098. PMID 29588983.

While you are restricting carbs, your fat intake will be used as a lever to increase and decrease calorie consumption so that you can gain, maintain, or lose weight. If you are eating the right protein along with the right amount of calories and fat, then the percentage of the weight you lose from fat will increase. It is possible to combine the results of several small studies to produce evidence that is stronger than that available from each study alone—a statistical method known as meta-analysis. One of four such analyses, conducted in 2006, looked at 19 studies on a total of 1,084 patients. [25] It concluded that a third achieved an excellent reduction in seizure frequency and half the patients achieved a good reduction. [18] a b Gano LB, Patel M, Rho JM. Ketogenic diets, mitochondria, and neurological diseases. J Lipid Res. 2014 Nov;55(11):2211–2228. doi: 10.1194/jlr.R048975. PMID 24847102.

The modified Atkins diet reduces seizure frequency by more than 50% in 43% of patients who try it and by more than 90% in 27% of patients. [18] While the strength of evidence is low for the modified Atkins, it has been known to show seizure freedom in some infants. [51] Few adverse effects have been reported, though cholesterol is increased and the diet has not been studied long term. [50] Although based on a smaller data set (126 adults and children from 11 studies over five centres), these results from 2009 compare favorably with the traditional ketogenic diet. [18] Low glycemic index treatment In 1994, Hollywood producer Jim Abrahams, whose son's severe epilepsy was effectively controlled by the diet, created the Charlie Foundation for Ketogenic Therapies to further promote diet therapy. Publicity included an appearance on NBC's Dateline program and ...First Do No Harm (1997), a made-for-television film starring Meryl Streep. The foundation sponsored a research study, the results of which—announced in 1996—marked the beginning of renewed scientific interest in the diet. [1] Using net carbs can allow additional room in your low carb diet for more nutrition from healthy carbs including: Fiber Normal dietary fat contains mostly long-chain triglycerides (LCTs). Medium-chain triglycerides (MCTs) are more ketogenic than LCTs because they generate more ketones per unit of energy when metabolised. Their use allows for a diet with a lower proportion of fat and a greater proportion of protein and carbohydrate, [18] leading to more food choices and larger portion sizes. [4] The original MCT diet developed by Peter Huttenlocher in the 1970s derived 60% of its calories from MCT oil. [15] Consuming that quantity of MCT oil caused abdominal cramps, diarrhoea, and vomiting in some children. A figure of 45% is regarded as a balance between achieving good ketosis and minimising gastrointestinal complaints. The classical and modified MCT ketogenic diets are equally effective and differences in tolerability are not statistically significant. [46] The MCT diet is less popular in the United States; MCT oil is more expensive than other dietary fats and is not covered by insurance companies. [18] Modified Atkins Most keto dieters will be able to meet their protein needs with 2-3 keto meals that contain one or more of these protein sources. If keto recipes aren’t enough to help you meet your protein needs, all you need to do is add one of the high protein foods from the list above.a b Epilepsies: diagnosis and management. National Institute for Health and Care Excellence (NICE). Published January 2012. Updated February 2016. Cited March 2018. ISBN 978-1473117907. Polyunsaturated fats (also known as PUFA’s) and are healthy fats ONLY when they come from natural sources. Fatty fish such as fresh salmon are healthy fats as are chia seeds. AVOID all polyunsaturated fats that are processed such as canola oil, sunflower oil, margarine, vegetable oil and shortening. Net carbs are also a helpful tool in allowing you to dig into sweet-tasting foods that are technically “sugar-free”. Sugar alcohols provide a sweet taste to food items without impacting net carb counts, thus making them an ideal keto diet-friendly dessert or low carb treat for diabetics. How to Calculate Net Carbs The BMR is simply a number of calories we burn while our bodies are at rest and from eating and digesting food. Together they form what’s known as TDEE, or total daily energy expenditure. This is the keto calculator’s estimate for your total calories burned per day. If you use a heart rate monitor or third party software to monitor your calories, you can use the custom input in the activity level section for an even more accurate macro profile. Porta N, Vallée L, Lecointe C, Bouchaert E, Staels B, Bordet R, Auvin S. Fenofibrate, a peroxisome proliferator-activated receptor-alpha agonist, exerts anticonvulsive properties. Epilepsia. 2009 Apr;50(4):943–948. doi: 10.1111/j.1528-1167.2008.01901.x. PMID 19054409.