If symptoms recur patients should revert to the starting dose. The lowest dose at which effective control of symptoms is achieved should be used. Budesonide is a type of medicine called a steroid (or corticosteroid). Steroids are a copy of a substance your body makes naturally. They're not the same as anabolic steroids. Follow the instructions that come with your medicine. Do not use more than the maximum number of sprays in 24 hours. The MHRA considers that there is no reason to believe that there is a higher risk of misuse for Benacort Hayfever Relief compared to other corticosteroid nasal sprays that are already classified as GSL. There is no evidence of abuse of these products since they were reclassified to GSL. Self-diagnosis

The metabolism of budesonide is primarily mediated by CYP3A enzymes. Co-treatment with CYP3A inhibitors, e.g. itraconazole, ketoconazole, clarithromycin, HIV protease inhibitors e.g. atazanavir, indinavir, nelfinavir, ritonavir and saquinavir, and cobicistat-containing products, are expected to increase the risk of systemic side effects (see section 4.4). Concomitant use of this product with HIV medicines is contraindicated (see section 4.3). The combination of this medicine with potent CYP3A inhibitors should be avoided unless the benefit outweighs the increased risk of systemic corticosteroid side effects, in which case patients should be monitored for systemic corticosteroid side effects. The interaction is of limited clinical importance for short-term (1-2 weeks) treatment with itraconazole or ketoconazole or other potent CYP3A inhibitors but should be taken into consideration during long-term treatment. If this medicine is co-administered with anti-fungals (such as itraconazole or ketoconazole), the period between treatments should be as long as possible. A reduction of the budesonide dose should be considered

Mixing budesonide nasal spray with herbal remedies and supplements

Patients should consult a physician if they develop signs or symptoms of an infection, such as persistent fever, while taking this medicine.

Benacort Hayfever Relief for Adults 64 micrograms, nasal spray is a medicine sprayed inside the nose for the treatment of seasonal allergic rhinitis (hayfever) in adults aged 18 years and over. At The Independent Pharmacy, we offer a range of hay fever and allergy treatments. This includes an alternative corticosteroid and antihistamine nasal sprays, antihistamine tablets, liquid solutions and eye drops designed to relieve hay fever symptoms that affect the eyes and nose as well as the rest of the body. Maintenance treatment with inhaled budesonide (200 or 400 micrograms twice daily) in asthmatic nursing women results in negligible systemic exposure to budesonide in breast-fed infants. In a pharmacokinetic study, the estimated daily infant dose was 0.3% of the daily maternal dose for both dose levels, and the average plasma concentration in infants was estimated to be 1/600th of the concentrations observed in maternal plasma, assuming complete infant oral bioavailability. Budesonide concentrations in infant plasma samples were all less than the limit of quantification. Budesonide nasal spray is available on prescription for adults and children aged 6 years old and over. You can also buy it from pharmacies and shops for adults aged 18 years old and over. They have severe or frequent nose bleeds, recent nose ulcers or nose surgery or a nose injury that has not healed.

Serious side effects

This evidence needs to focus on the risk to the public. This includes evidence on the possible abuse or misuse of the medicine. The evidence may include: The MHRA considers this product sufficiently safe to be sold on general sale. This report outlines the evidence that the MHRA reviewed and which led to the decision to approve the application. 2.1 What is in Benacort Hayfever Relief?

If you take too many doses of Benacort® Hayfever Relief, talk to your doctor or pharmacist straight away. Additional risk minimisation measures have been added to the RMP to reflect the GSL classification including: Budesonide is moderately lipophilic and systemic exposure is primarily due to its rapid absorption through the nasal mucosa. The systemic bioavailability of budesonide following intranasal administration is 6 to 16%. The Global post-marketing data between December 2013 to April 2017 and USA Post-marketing data from 01 January 2016 to 30 April 2017 (which is mostly data on non-prescription use) did not raise any concerns which would affect the proposed reclassification to GSL.If you forget to use your nasal spray just leave out the forgotten dose. Don't use a double dose to make up for a missed dose. Put the tip of the nozzle into 1 nostril, being careful to keep it pointing towards the side of the nostril and not the middle (nasal septum). Gently shake the bottle, remove the cap and keep upright. Pump the nozzle until it starts to spray mist.

In animal reproduction studies, corticosteroids such as budesonide have been shown to induce malformations (cleft palate, skeletal malformations). However these animal experimental results do not appear to be relevant in humans at the recommended doses. GSL medicines for the treatment of hayfever have been available for decades. Therefore, a patient’s ability to self-diagnose hayfever has already been established. Risk of misdiagnosis or delayed diagnosis of a more serious conditionDo not use the spray more often, or for a longer period of time, than is recommended by your doctor or pharmacist. This could increase the risk of side-effects.