TRU NIAGEN Niacin as Nicotinamide Riboside NAD+ Supplement for Reduction of Tiredness & Fatigue, Patented Formula NR - 120 Count 150mg

Product Information

Liao, B., Zhao, Y., Wang, D., Zhang, X,. Hao, X., & Hu, M. (2021). Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. Journal of the International Society of Sports Nutrition, 18, 54. Highly effective molecular precursors for NAD+. The precursors we looked for included tryptophan, nicotinamide riboside, nicotinic acid riboside, niacin (also known as vitamin B3), and nicotinamide mononucleotide. As the names suggest, these are all related but different compounds, and all of them can serve as precursors to NAD+ ( 3 ). Navas, L. E., & Carnero, A. (2020). NAD+ metabolism, stemness, the immune response, and cancer. Signal Transduction and Targeted Therapy, 6(1), 1-20. Tummala, K. S., Gomes, A. L., Yilmaz, M., Graña, O., Bakiri, L., Ruppen, I., Ximénez-Embún, P., Sheshappanavar, V., Rodriguez-Justo, M., Pisano, D. G., Wagner, E. F., & Djouder, N. (2014). Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage. Cancer Cell, 26(6), 826–839. Fania, L., Mazzanti, C., Campione, E., Candi, E., Abeni, D., & Dellambra, E. (2019). Role of Nicotinamide in Genomic Stability and Skin Cancer Chemoprevention. International Journal of Molecular Sciences, 20(23).

There’s an all-important molecule called NAD+ that’s vital to cellular function. It’s depleted by stressors, too, and also declines naturally as you age. Take up the fight against stressors. Reclaim energy for your 37.2 trillion cells. Transform the way you age starting today. NMN, or nicotinamide mononucleotide, has shown promise in animal studies, but when it comes to human studies, the best evidence we have right now points towards nicotinamide riboside. That’s why our top-ranked NAD+ supplements, like Elysium Basis and TRU Niagen, are nicotinamide riboside-based. Toniiq makes one of the best NAD+ supplements that uses nicotinamide mononucleotide as its NAD+ precursor. These ultra-simple capsules provide 150 mg of nicotinamide mononucleotide each, with a few binders and stabilizers as well. Boosting NAD+ levels with an NAD+ supplement could be a way to reverse some of these aging-related declines. NAD+ supplements focus on some of the core mechanisms of aging, as opposed to superficial aging treatments like wrinkle cream , which only target a specific manifestation of the aging process (in that case, loss of collagen in the skin).Genex Formulas is a nicotinamide mononucleotide-based formula, which provides 125 mg of this vitamin B3 derivative in each capsule. Genex Formulas claims that nicotinamide performs best when paired with resveratrol, but puzzlingly, does not actually include any in the supplement. As you can see, Tru Niagen Immune also contains 150mg of NR. This presents an exciting opportunity for those who want to maximize their NAD production. Tru Niagen says that it designed Immune for you to take in conjunction with standard Tru Niagen. Together, that would give you a 450mg daily dose of NR. That’s nearly the amount in Tru Niagen Pro, which is much harder to come by.

Day in and day out, your cells are also in constant conflict with stressors great and small. In this conflict, they incur damage. On the one hand, a 2014 study of NR on mice showed that supplementation with NR helped protect the mice against liver cancer. 10 And on the other, continuing research demonstrated successful tumor growth inhibition by reducing NAD. 11 Further NAD studies in human subjects with known cancers can help researchers determine how an increase in NAD can affect tumor size and spread. Scientific NAD+ Gold uses NMN, or nicotinamide mononucleotide, to boost NAD+. This compound has demonstrated better performance than nicotinamide when it comes to sustaining high NAD+ levels, at least in animal studies, so it’s a good choice for a sublingual spray. 4. Corllia Liposomal NAD+ A 2014 study found that NR supplementation protected mice against certain types of liver cancer. 10 NAD allows other beneficial enzymes to work more effectively within the body, such as: 12

Customers also viewed

With capsules, we had a slight preference for vegan-friendly cellulose over gelatin capsules, but in most cases the top supplements already were using vegetable-derived cellulose. While Tru Niagen traditionally focused on its nicotinamide riboside supplement alone, the company has since added a new product to its lineup: Tru Niagen Immune. It contains a small handful of vitamins and minerals that research shows play significant roles in immune system performance. However, the star of the ingredients list is an altered form of curcumin called Theracurmin. NAD’s potential to improve mitochondrial function and overall cellular health makes it an interesting choice for the general population, but certain demographics stand to benefit even more than the average person. Those over 60 will see significant declines in their NAD levels and are at a point in their lives where disease risks rise sharply. Bolstering cellular function at advanced ages can potentially stave off these issues. There’s also evidence that NAD supplementation can improve exercise performance, and good exercise habits are essential to longevity. Your lifestyle matters too. Stressors and certain lifestyle choices (like maintaining an unhealthy diet and drinking alcohol, for instance) can also deplete your body’s supply of NAD. 17

Nicotinamide mononucleotide (NMN) is a compound that’s incredibly similar to NR, and both have been shown to raise NAD levels in studies. 14 The argument in favor of NMN has to do with absorption, as there’s some disagreement in the scientific community as to which compound — NR or NMN — absorbs better. A: Both niacin and niacinamide are easily absorbed by your body, and your body can convert niacin into niacinamide. While both of these forms of vitamin B3 have been studied for their potential to boost NAD+ levels, neither of them are the most-researched compounds for increasing NAD+ these days. Instead, much of the focus is now on nicotinamide mononucleotide and especially nicotinamide riboside. Until that research is done, it might be wise for anyone with cancer or who has recently survived cancer to avoid NAD-boosting supplements. Those with a history of cancer in their families might also want to consider waiting until more research comes in. The chief reason that NR supplementation would be good for you is that NR is an NAD precursor in our bodies. In other words, ingesting Niagen replenishes our body's NAD supply.It’s an interesting idea, but most of the scientific research right now indicates that the most effective way to boost NAD+ is with precursors, not NAD+ itself. Category winners Thorne ResveraCel provides nicotinamide riboside for NAD+ alongside the powerful antioxidants quercetin, resveratrol, and betaine. This potent combo is great for older adults looking to fight inflammation and oxidative damage, and it doesn’t skimp on the NAD+ dosage even though it has other active ingredients. Biom Pharmaceuticals is one of the few companies to provide actual NAD+ in their supplement. Capsule-based supplements can’t do this because NAD+ isn’t bioavailable in the stomach, but Biom Pharmaceuticals is banking on sublingual absorption of NAD+ into your bloodstream.