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Kwok JS, Chan IH, Chan MH. Biotin interference on TSH and free thyroid hormone measurement. Pathology. 2012;44(3):278-80. View abstract. Contains vitamins C, B6, B12, D and Biotin for normal hormonal activity & maintenance of normal bones to contribute to normal energy release CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
Ebek, Inc. issues voluntary nationwide recall of Liviro3, a product marketed as a dietary supplement. Ebek Press Release, January 19, 2007. Available at: https://www.fda.gov/oc/po/firmrecalls/ebek01_07.html.There are some cases where certain dietary or other habits have caused a deficiency of biotin. Studies have found that women who smoke can increase the metabolism of biotin in their bodies and cause a deficiency. Sulaiman RA. Biotin treatment causing erroneous immunoassay results: A word of caution for clinicians. Drug Discov Ther 2016;10(6):338-9. View abstract. Camacho FM, Garcia-Hernandez MJ. Zinc aspartate, biotin, and clobetasol propionate in the treatment of alopecia areata in childhood. Pediatr Dermatol 1999;16:336-8. View abstract. Third-party testing. It’s best to choose a supplement that has undergone third-party testing to ensure quality and purity. Many supplements on this list are third-party tested, and the rest are manufactured in CGMP certified facilities with in-house testing protocols. Aldahmash BA, et al. (2015). Biotin ameliorationof nephrotoxicity in streptozotocin-induced diabetic mice. DOI:
Future studies are needed to determine whether biotin supplements might improve hair, nail, and skin health, especially among healthy individuals. Health Risks from Excessive Biotin
Biotin supplements
Green NM. Avidin. 1. The use of (14-C)biotin for kinetic studies and for assay. Biochem. J. 1963;89:585-591. View abstract. Very high intakes of biotin may interfere with diagnostic assays that use biotin-streptavidin technology and are commonly used to measure levels of hormones (such as thyroid hormone) and other analytes such as 25-hydroxyvitamin D, producing falsely normal or abnormal results [ 9, 32]. As a result, a few recent case reports have described findings falsely indicating Graves' disease and severe hyperthyroidism in patients taking 10–300 mg biotin per day, including six children receiving high doses of biotin (2–15 mg/kg body weight per day) to treat inherited metabolic diseases [ 33-37].
Remember, however, that biotin may interfere with lab testing results. Biotin supplements may also interfere with anticonvulsant medications, so make sure to speak with a healthcare professional before taking biotin if you’re on an anticonvulsant ( 1). How to tell if you need more biotin? Krause KH, Berlit P, Bonjour JP. Impaired biotin status in anticonvulsant therapy. Ann Neurol 1982;12:485-6. [ PubMed abstract]Well, studies have found that biotin can improve the keratin infrastructure within our bodies. How this actually happens, and how biotin helps hair and skin health, is still very much a mystery.
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