Boswellia Serrata Extract 3000mg - 65% Boswellic Acid (150mg per Capsule) - Indian Frankincense - 60 Vegan Capsules (2 Months Supply)

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The resin that is secreted naturally to protect the Boswellia tree is tapped and purified for use in powder form. This gum tree resin consists of essential oils, gum, and terpenoids. The terpenoid portion contains the boswellic acids that have been shown to be the active constituents within Boswellia. Etzel R. Special extract of Boswellia serrata (H 15) in the treatment of rheumatoid arthritis. Phytomedicine 1996;3:91-4.. The Arthritis Foundation recommend taking approximately 300–400 milligrams (mg) of boswellia three times per day to deliver boswellic acids to the body. They recommend looking for capsules that contain 60% boswellic acid, as it is the active ingredient. Boswellia for dogs and cats plays an important role in maintaining healthy joint function, which can impact a pet’s everyday life. Kesava, Reddy G., Dhar, S. C., and Singh, G. B. Urinary excretion of connective tissue metabolites under the influence of a new non-steroidal anti-inflammatory agent in adjuvant induced arthritis. Agents Actions 1987;22(1-2):99-105. View abstract.

Hostanska, K., Daum, G., and Saller, R. Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro. Anticancer Res. 2002;22(5):2853-2862. View abstract. Kulkarni PD, Damle ND, Singh S, et al. Double-blind trial of solid lipid Boswellia serrata particles (SLBSP) vs. standardized Boswellia serrata gum extract (BSE) for osteoarthritis of knee. Drug Metab Pers Ther. 2020;35(2):/j/dmdi.2020.35.issue-2/dmpt-2020-0104/dmpt-2020-0104.xml. View abstract. Kirste S, Treier M, Wehrle SJ, et al. Boswellia serratea extract acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. Cancer 2011;117:3788-95. View abstract. Takada, Y., Ichikawa, H., Badmaev, V., and Aggarwal, B. B. Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression. J Immunol 3-1-2006;176(5):3127-3140. View abstract.Kumar, R., et al. (2019). Effect of boswellia serrata extract on acute inflammatory parameters and tumor necrosis factor-α in complete Freund's adjuvant-induced animal model of rheumatoid arthritis. Zhao, W., Entschladen, F., Liu, H., Niggemann, B., Fang, Q., Zaenker, K. S., and Han, R. Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells. Cancer Detect.Prev. 2003;27(1):67-75. View abstract. https://www.researchgate.net/publication/12466811_Randomized_double_blind_trial_of_an_Ayurvedic_plant_derived_formulation_for_treatment_of_rheumatoid_arthritis In addition, Boswellia is believed to play a role in maintaining healthy matrix metalloproteinase (MMP) activity, which supports connective tissue structural composition. MMPs, are a large group of (zinc dependant) enzymes which cleave the constituents of the extracellular matrix and are thought to play a role in joint destruction. Boswellia for dogs, cats and horses

Skin Inflammation –Boswellia serrata can be used topically and is a common ingredient in traditional preparations of makeup and cosmetic products, but it can result in skin inflammation in some people. These types of allergic reactions are relatively rare and can be avoided by using small amounts of these products first and waiting to see if any negative reactions occur. [15]Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. View abstract.

Yu G, Xiang W, Zhang T, Zeng L, Yang K, Li J. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. BMC Complement Med Ther. 2020;20(1):225. View abstract. Roy, S., Khanna, S., Shah, H., Rink, C., Phillips, C., Preuss, H., Subbaraju, G. V., Trimurtulu, G., Krishnaraju, A. V., Bagchi, M., Bagchi, D., and Sen, C. K. Human genome screen to identify the genetic basis of the anti-inflammatory effects of Boswellia in microvascular endothelial cells. DNA Cell Biol 2005;24(4):244-255. View abstract. Sarkate A, et al. (2017). Investigation of mitigating effect ofcolon-specific prodrugs of boswellic acid on 2,4,6-trinitrobenzene sulfonicacid-induced colitis in Wistar rats: Design, kinetics and biologicalevaluation. DOI: Flavin, D. F. A lipoxygenase inhibitor in breast cancer brain metastases. J Neurooncol. 2007;82(1):91-93. View abstract.Xia, L., Chen, D., Han, R., Fang, Q., Waxman, S., and Jing, Y. Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells. Mol.Cancer Ther 2005;4(3):381-388. View abstract. Gupta I, Gupta V, Parihar A, et al. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res 1998;3:511-4. View abstract.