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Gholnari T, et al. (2018). The effects of Coenzyme Q10 supplementation on glucose metabolism, lipid profiles, inflammation, and oxidative stress in patients with diabetic nephropathy: A randomized, double-blind, placebo-controlled trial. Some research suggests that CoQ10 might help ease muscle weakness that is due to taking cholesterol-lowering medications, known as statins.
In exercise, the need for cellular energy is obvious: better energy production means you can run faster and lift more. Studies show that supplementing with CoQ10 helps reduce the production of free radicals, which are unstable molecules that can harm your health if their numbers get too high. However, other studies have shown no effect, emphasizing the need for more research on this topic ( 12). In terms of its actual health effects, CoQ10 boosts performance in high intensity workouts that rely on high levels of aerobic power output. Ubiquinone and ubiquinol are the two forms of CoQ10. Ubiquinone, also known as ubidecarenone, is primarily found in animals and bacteria, while bodies naturally produce ubiquinol, says Dunham. Schachter further explains that ubiquinone is the oxidized form, and ubiquinol is the reduced form. They both state that ubiquinol is generally the most bioavailable and absorbable form; however, most supplements contain ubiquinone.It’s also been studied as a way to prevent or slow the progression of cognitive decline among elderly adults, with the goal of supporting energy production in the brain, and to prevent the deterioration of brain cells over time. CoQ10 has been shown to have a potentially positive effect on fertility, specifically male fertility. Studies have shown doses between 200 mg and 400 mg of daily CoQ10 supplementation may help improve sperm count and motility. If improving fertility is your primary concern for a CoQ10 supplement, we recommend GNC’s CoQ10 200 mg option. These third-party tested softgels are pretty small in size, so they are easy to swallow. Whether a 200mg or 400mg dose has been recommended for you, these softgels can be an easy way to meet your needs. Just because a supplement is not tested by one of these three companies, it does not mean it’s a bad product. We recommend doing some research on the reputability of the manufacturer and calling up the manufacturer and their testing lab to determine their protocols and decide if you feel comfortable consuming the supplement. For people taking statin medications, the typical dosage recommendation for CoQ10 is 30–200 mg per day ( 13). Heart Disease
Transparent Labs produces an effective and pure CoQ10 designed for reliable long-term use at 100 mg per serving. CoQ10 plays a few critical roles in the body. For example, the body’s cells need this compound to produce the energy that allows them to function. Manzar H, et al. (2020). Cellular consequences of Coenzyme Q10 deficiency in neurodegeneration of the retina and brain.CoQ10 supplements are considered safe for most people with a relatively low risk for any side effects. The side effects that have been reported—insomnia and digestive upset—are mild and usually reported with higher doses. Breaking up dosage throughout the day can help. Hernández-Camacho JD, Bernier M, López-Lluch G, Navas P. Coenzyme q10 supplementation in aging and disease. Front Physiol. 2018;9:44. doi:10.3389/fphys.2018.00044
Rodriguez-Varela C & Labarta E. (2021). Does Coenzyme Q10 supplementation improve human oocyte quality?Additionally, be sure to buy supplements that deliver CoQ10 in the form of ubiquinol, which is the most absorbable ( 44). Summary Oxidative stress can interfere with regular cell functioning and may contribute to many health conditions. Therefore, it is not surprising that some chronic diseases have also been associated with low levels of CoQ10. Simple capsules. To broaden the accessibility of our top-rated products, we had a preference for vegetable-based cellulose capsules over gelatin.
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