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The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease

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Women with children: differences associated with processing and responding to social signals. (p.46). Women with children develop a sleep debt (p. 48) and often experience “reduced performance on memory tests that place a high demand on free recall and working memory”. Memory difficulties worsen depending on the number of children. (p.47). Alzheimer's Disease is one of the biggest threats to women's health, and there is so much that we *can* do to minimize our risks, especially during these hormone rollercoaster years. We are constantly exposed to substances that mess with our hormones. Up to 25 percent of the pesticides sprayed on non-organic fruit and vegetables are known to disrupt the body’s estrogen balance. And chapter 1 ends with a paragraph explaining that transwomen and the aging brain is not well researched. (p.14) Does not mention that women without children and their aging brains is not well researched, so why are they not mentioned? Men’s brains produce more serotonin and women’s produce more dopamine. Men’s brains have more M cells to detect movement while women’s have more P cells to detect shapes.

In The XX Brain, Lisa meticulously guides us in the ways we can both nourish and protect ourselves, body and mind, to ensure our brains remain resilient throughout our lives.” I am so happy to finally read a book about the female brains by a female neurologist, nutritionist and PhD. It's about time! I happened to stumble upon this phenomenal book, and I wish I could recommend it to every woman I know who is on the struggle bus with all of this hormone nonsense. In terms of cardiovascular disease and type 2 diabetes 80 percent or more is caused by dietary choices, weight control and physical activity (or other unhealthy lifestyle factors). (p 18) This is a groundbreaking, must-read book, right on target with what I have found about women’s brains.As we age it is critical for us to act aggressively in promoting not just our health but our brain health through lifestyle. I highly recommend it!” —Anna Cabeca, DO, author of The Hormone Fix

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Inflammation: against bacteria, cancer, dental abscess for example (p.34 to 35). Presence of chronic inflammation related to cognitive decline (p. 32). Suggestion: Avoid things that increase inflammation and practice those things that decrease it. (p.35). Suggestions for this: eat well, exercise, rest and sleep, lose weight if needed, quit smoking. Reduce or eliminate exposure to toxins and get treatment if needed, if cholesterol is high – lower it, get treatment for harmful bacterial and for gum disease.

Popular wisdom about what we should eat is always changing. In the early 1990s, low-fat diets were gospel; today high-fat “keto” diets are all the rage. The truth is, no extreme diet is healthy for your brain. Instead, focus on the quality of the food you eat. New research indicates that reducing caloric intake can boost cognitive capacity, reduce cellular aging, and promote longevity. Nearly a century of data shows that stressing our bodies and brains by restricting calories — within reason! — pushes cells to grow stronger and more resilient. Caloric restriction also boosts the brain’s antioxidant defense system, important for the female brain. It’s also a great way to lose a few pounds, if you need to, and keeping a healthy, stable weight is beneficial for women.

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That said, for most women, some wine is OK, especially if it’s red. Red wine has high levels of resveratrol, an antioxidant. If you’re someone for whom alcohol is advised, a five-ounce glass of wine once in a while (but no more than once a day) can be good for you. Antioxidants are vitamin-warriors that fight free radicals. Amongst the most powerful are vitamins C, E, beta-carotene and selenium and plant-made nutrients like lycopene and anthocyanins. Our research shows that an antioxidant-rich diet is associated with steady brain energy levels and fewer Alzheimer’s plaques, especially in women. It can seem like Alzheimer’s comes on suddenly, but the disease is decades in the making. While the clearest symptoms may only be visible in old age, the groundwork is laid when we’re young. For many women, menopause is when it begins. Mosconi covers everything from brain fog, memory lapses, depression, stress, insomnia, hormonal imbalances, and your increased risk of dementia. It is a book full of information, an interesting read and the author has spent her life researching women and their health issues...I was amazed to read that clinical trials were given to men and not women...just a few years ago. The male medical profession is learning (albeit it slowly) about women. The disparity is not only financially but also includes intellectual, legal and medical areas. This outstanding book will provide the reader with some important tools to assist them.

Women over 35 need to know that perimenopause is a dramatic transition state not just in terms of mood, sex drive, and hot flashes—but in terms of brain health and function. Lisa Mosconi is the leading authority on the female brain as it navigates hormonal upheaval, and she is here to close our knowledge gap. I give her extraordinary new book my highest recommendation!" —Sara Gottfried, MD, New York Times bestselling author of The Hormone Cure Some people avoid fruits due to sugar, but many fruits are supportive of memory and mental acuity thanks to high vitamin and antioxidant content. If you are concerned about sugar, choose low glycemic fruits like berries, apples, lemons, oranges, grapefruit and even watermelon.

Adopting a brain-healthy diet is a powerful tool in maximizing cognitive health and helping prevent dementia and Alzheimer’s disease, says neuroscientist and nutritionist Lisa Mosconi. What’s more, it may even ward off common ailments that affect many women, from slow metabolism to insomnia and depression. Here are 8 steps to take.

Alzheimer’s she argues is similar and she recommends : a good diet and exercise, conscientious intellectual and social engagement, stress reduction, better sleep, balancing hormones, avoiding smoking and toxin exposure, management of cardiovascular health and preventing obesity and diabetes. (p.18) Look for these veggies: dark leafy greens (spinach, Swiss chard, kale) and cruciferous veg (broccoli, cauliflower). Studies show that people who consume 1-2 servings of leafy greens each day experience fewer memory problems and cognitive decline than people who rarely eat them1. Low to medium glycemic vegetables such as onions, beets, pumpkin and carrots are also good. Women metabolize medicine differently to men as well. Researchers found that the recommended daily dose of the sleeping pill Ambien is actually harmful to women because – you guessed it – the dose was tested on men. In The XX Brain , Lisa meticulously guides us in the ways we can both nourish and protect ourselves, body and mind, to ensure our brains remain resilient throughout our lives." Women have 11 percent more neurons in the primary auditory cortex, resulting in better hearing than men.

Women also can benefit from monounsaturated fat from nuts such as almonds, cashews, hazelnuts, pistachio and Brazil nuts; fatty fruit (avocado and olives); and some oils and nut butters from sesame and sunflower seeds. Step 5: Feed your microbes By eating a balanced diet of high-quality foods and supplementing where you need to, you’ll allow your body – and brain – to flourish. Reality: Don’t believe that genes are destiny. Do believe that our medical health, our environment and the choices we make, are important. (p.17). The exception is for about 1-2% of people who are likely due to genetics to get early onset dementia. But that means about 98-99% of people are not in this group. (p.17)The XX Brain is a must read for every woman who wants to protect her brain. Dr Mosconi presents invaluable information and practical solutions to be—and stay—your best." —Louann Brizendine MD, New York Times bestselling author of The Female Brain Stuff to get tested for and treat: UTIS, herpes, STIs such as syphilis and HIV. Also watch out for Epstein-Barr virus, Lyme disease and babesia (p.35)

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