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Antimuscarinic drugs: May have an additive muscarinic action with other drugs such as atropine and some antidepressants.There have been rare cases of posterior reversible encephalopathy syndrome (PRES)/reversible cerebral vasoconstriction syndrome (RCVS) reported with sympathomimetic drugs, including pseudoephedrine. Symptoms reported include sudden onset of severe headache, nausea, vomiting, and visual disturbances. Pseudoephedrine should be discontinued, and medical advice sought immediately if signs or symptoms of PRES/RCVS develop. The globalisation of world business in the last 5 decades has heralded in an era when cultural differences have become vitally important to leaders, managers and executives in the world’s international and multinational companies. The complexities of merging corporate cultures, issues of leadership, planning, decision-making, recruitment and task assignment are all compromised by the nation-traits of the people involved. What allowances must be made when outlining organisational culture? Where can one look for guidelines?

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