Follow-up should be performed/coordinated by a physician experienced with follow-up care after radiotherapy and BT including monitoring of early, and late treatment-related side effects [V, A].

Diagnosis of T1a cancer should be based on a conization (or excision) specimen examined by an expert pathologist with accurate measurement of depth of invasion, margin status, coexisting pathology, and reliable assessment of LVSI [IV, B]. Quantum Nutrition Labs is proud to offer a high-quality nutritional product line tomeet all the needs of you and your family. We provide a wide range of quantum-state nutritional formulas, including Quantum Estro Support . Our products are manufactured and diligently tested for identity, purity, strength, and nutrient content, as well as for potential contaminants such as pesticides, non-organic materials, and heavy metals including arsenic, mercury, cadmium and lead, that may negatively impact health. These ultra-quality products provide you with full confidence in our company ’s integrity that you can count on . . . day in and day out. Execute all communication requests from external partners in accordance with ESTRO's support policy.Histopathological diagnosis of rare cervical tumors needs confirmation (second opinion) by an expert pathologist [IV, A]. The ambition of ESTRO to further reinforce radiation oncology as a core partner in multidisciplinary cancer care, and to guarantee accessible and high-value radiation therapy for all cancer patients who need it, is expressed in the society’s vision statement for 2030: ‘Radiation Oncology. Optimal Health for All, Together.’. After a challenging couple of years, it is more important than ever before to gather as a community to connect, share and learn.

If SLN is negative bilaterally in the pelvic level I area (below iliac bifurcation) LN dissection can be limited to level I [IV, B]. Type C radical hysterectomy is recommended. LN staging should follow the same principles as in T1b1-2 tumors [IV, A]. Every patient diagnosed with cervical cancer in pregnancy must be counseled by a multidisciplinary team. This team should consist of experts in the fields of gynecological oncology, neonatology, obstetrics, pathology, anesthesiology, radiation oncology, medical oncology, psycho-oncology, and, spiritual and ethical counseling. National or international tumor board counseling may be considered [V, A]. Intraoperative placement of permanent cerclage should be performed during simple or radical trachelectomy [IV, B]. Amanda Webster (UK), Ben Slotman (NL), Daan Nevens (BE), Ester Hammond (UK), Ina Schulz-Jurgenliemk (NL), Jens Overgaard (DK), Ludvig Muren (DK), Ludwig Van den Berghe (BE), Marianne Aznar (UK), Michael Baumann (DE), Michelle Leech (IE), Pierre Blanchard (FR)Resveratrol Reduces oxidative stress and inflammation to improve general health. Plus, can help increase insulin sensitivity to minimise blood sugar spikes and improve focus. Early palliative care, integrated with oncological treatments, should be offered by the clinical team to all the patients diagnosed with advanced cervical cancer for managing symptoms and improving quality of life. A multidisciplinary approach must be included in the care plan with discussion and planning for specific treatment of these symptoms [IV, A]. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. If opioids alone do not provide sufficient pain relief cancer-related neuropathic pain should be treated with a combination of opioids and carefully dosed adjuvants (gabapentin, pregabalin, duloxetine, and tricyclic antidepressants) [III, B]. The aim of the diagnostic work-up is to determine the extent of the locoregional and/or metastatic disease [V, B].

The patient should be carefully counseled regarding treatment options, risks and consequences [V, A]. Opioids are the main analgesics for the treatment of moderate to severe cancer-related pain; the first option is oral morphine [I, A]; but other opioids and alternative routes (transdermic, subcutaneous) can be required in specific situations (ie, intestinal obstruction, problems with swallowing, renal failure) [III, B]. Specimens from prior conization and subsequent conization, trachelectomy, or hysterectomy should be correlated for estimation of the tumor size. This is important since different specimens may have been reported at different institutions. It should also be recognized that simply adding the maximum tumor size in separate specimens may significantly overestimate the maximum tumor dimension. Histological tumor type according to the most recent WHO classification (currently 5th edition, 2020, in its updated version). Previous pertinent histological exams of the cervical lesion/cancer, even if diagnosed in another institution, should be revised and integrated in the final report (eg, cone biopsy and hysterectomy specimen)Arbyn M, Weiderpass E, Bruni L et al (2020) Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health 8:e191-203

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HOW TO USE ESTRO SUPPORT?

Develop and execute comprehensive marketing plans for ESTRO activities, tailoring strategies to specific target audiences, and concurrently manage social media messaging, content schedules, and event planning. In patients with cervical advanced cancer, a multidisciplinary approach of physicians, nurses, psychologists, social workers, and community health workers is needed to manage psychosocial and spiritual suffering associated with social stigma deriving from genital disease, malodorous vaginal discharge, etc [IV, A].