Tot unguentul se folosește și în caz de arsuri de gradul 2, deoarece asigură o umiditate mai mare decât spray-ul și astfel ajută la vindecare arsurilor severe. De asemenea, unguentul poate fi utilizat și în caz de leziuni cutanate atrofice, deoarece conține clohexidină, o substanță cu efecte antispetic ce previne apariția infecțiilor. Când se folosește Cicatridina spray? Long-term topical treatment of rats with tacrolimus led to systemic toxicity including alterations of kidneys, pancreas, eyes and nervous system. The changes were caused by high systemic exposure of rodents resulting from high transdermal absorption of tacrolimus. Slightly lower body weight gain in females was the only systemic change observed in micropigs at high ointment concentrations (3%).

a de aplica Cicatridina cremă sau spray pe zona afectată, trebuie curățată foarte bine pielea. De asemenea, și mâinile trebuie spălate bine atât înainte cât și după aplicarea unguentului și a spray-ului. CICATRIDINA ® αλοιφής σε συνδυασμό με άλλα ιατροτεχνολογικά προϊόντα ή φάρμακα για τοπική δερματολογική χρήση. Cicatridine Hyaluronic Acid Cream for External Use 30 grams is indicated for vaginal yeast infections, vaginal dryness and traumatic injuries . This cream based on hyaluronic acid acts as structural support and therefore gives tone and elasticity to the tissues. Cicatridine Hyaluronic Acid Cream for External Use 30 grams promotes local vaginal healing. It is an adjuvant treatment of the process of superficial and deep wounds (abrasions, lacerations, burns, surgical wounds, decubitus wounds and ulcers). This cream is formulated without parabens.In a photocarcinogenicity study, albino hairless mice were chronically treated with tacrolimus ointment and UV radiation. Animals treated with tacrolimus ointment showed a statistically significant reduction in time to skin tumour (squamous cell carcinoma) development and an increase in the number of tumours. It is unclear whether the effect of tacrolimus is due to systemic immunosuppression or a local effect. The risk for humans cannot be completely ruled out as the potential for local immunosuppression with the long-term use of tacrolimus ointment is unknown. The use of tacrolimus ointment is not recommended in patients with a skin barrier defect, such as Netherton's syndrome, lamellar ichthyosis, generalized erythroderma or cutaneous Graft Versus Host Disease. These skin conditions may increase systemic absorption of tacrolimus. Post-marketing cases of increased tacrolimus blood level have been reported in these conditions. Protopic should not be used in patients with congenital or acquired immunodeficiencies or in patients on therapy that cause immunosuppression. Rabbits were shown to be especially sensitive to intravenous administration of tacrolimus, reversible cardiotoxic effects being observed. Care should be exercised if applying Protopic to patients with extensive skin involvement over an extended period of time, especially in children (see section 4.2).

Ingrediente Cicatridina spray– octenisluccinat de amidon și aluminiu, hexamtildisiloxan, vitamina E acetat, ulei de migdale dulci, ximeninic, ulei esențial de arbore de ceai, acid hialuronic, butan, isobutan, propan. Based on the results of long-term studies and experience a link between Protopic ointment treatment and development of malignancies has not been confirmed, but definitive conclusions cannot be drawn. It is recommended to use tacrolimus ointment at the lowest strength and the lowest frequency for the shortest duration necessary as determined by the physician's evaluation of the clinical condition (see section 4.2). The incidence and nature of most adverse events were similar in the two treatment groups. Skin burning, herpes simplex, alcohol intolerance (facial flushing or skin sensitivity after alcohol intake), skin tingling, hyperaesthesia, acne and fungal dermatitis occurred more often in the tacrolimus treatment group. There were no clinically relevant changes in the laboratory values or vital signs in either treatment group throughout the study. The efficacy and safety of Protopic was assessed in more than 18,500 patients treated with tacrolimus ointment in Phase I to Phase III clinical trials. Data from six major trials are presented here.Cicatridina είναι μια κρέμα με υαλουρονικό νάτριο που προάγει την επιθηλιοποίηση του δέρματος, προάγοντας τη γρήγορη ανάπλαση και επούλωση του δέρματος. Emollients should not be applied to the same area within 2 hours of applying Protopic ointment. Concomitant use of other topical preparations has not been assessed. There is no experience with concomitant use of systemic steroids or immunosuppressive agents. It should not be administered to newborns and premature infants during the first 2 months due to an increased risk of kernicterus.

Data from healthy human subjects indicate that there is little or no systemic exposure to tacrolimus following single or repeated topical application of tacrolimus ointment. Cicatridine cream comes in the form of a 30g tube. Keep the medical device tightly closed, away from light and heat. Learn more about hyaluronic acid Durata utilizarii depinde de evolutia simptomelor; daca este necesar, unguentul CICATRIDINA poate fi utilizat pentru lungi perioade de timp. The safety of CICATRIDINA ointment during pregnancy and lactation has not been proven. Therefore, it is recommended that you consult your doctor before using this product.Patients, particularly paediatric patients should be continuously evaluated during treatment with Protopic with respect to the response to treatment and the continuing need for treatment. After 12 months this evaluation should include suspension of Protopic treatment in paediatric patients (see section 4.2). The effect of treatment with Protopic ointment on the developing immune system of children aged below 2 years has not been established (see section 4.1). Cicatridina ενδείκνυται για την επικουρική θεραπεία και ανάπλαση δέρματος σε περιπτώσεις τραυμάτων, πληγών, εκδορών, εγκαυμάτων, αιμορροΐδες, έλκη κατάκλισης κ.α. The active substance in the medicinal product is silver sulfadiazine. It breaks down in the wound so that the slow release of silver ions begins. They aim to suppress bacterial cells growthand multiplication, stopping the infection. The ions do not damage the skin and tissue. Systemic carcinogenicity studies in mice (18 months) and rats (24 months) revealed no carcinogenic potential of tacrolimus. Toată lumea visează să aibă o piele de invidiat, însă micile accidente casnice, ne pot lăsa semne pentru tot restul vieții.