Because chewable CBD gummies must go through first-pass metabolism before the remaining CBD is absorbed into the bloodstream—and everyone’s metabolism functions slightly differently—it’s difficult to pinpoint a precise amount of time in which the effects of CBD gummies take place (and likely varies from person to person depending on potency and the amount ingested).

Xu DH, et al. (2020). The effectiveness of topical cannabidiol oil in symptomatic relief of peripheral neuropathy of the lower extremities.Sultan SR, et al. (2020). The effects of acute and sustained cannabidiol dosing for seven days on the haemodynamics in healthy men: A randomised controlled trial. Sometimes other ingredients are added for taste, consistency, and other health benefits. If you’re looking for a product that has a particular flavor, you might want to look for one with added essential oils or flavorings. Beware of any company that promises extreme results, and remember that results may differ. A product that works well for a friend or family member may not have the same effects for you. Lucas P, et al. (2021). Cannabis significantly reduces the use of prescription opioids and improves quality of life in authorized patients: Results of a large prospective study.

Because CBD may cause side effects, such as drowsiness or lightheadedness, individuals may want to avoid consuming CBD when taking over-the-counter or prescription medications like opioids, benzodiazepines, antipsychotics and antihistamines or alcohol to reduce the risk of increased tiredness, fatigue, accidental falls or accidents while driving. Consuming CBD alongside supplements like melatonin, St. John’s wort and kava may also increase feelings of drowsiness or sedation. If you don’t mind the strong bitter taste, The Original Alternative is another great option. 6. Bud & Tender The jury is still out on whether CBD topicals offer up definitive pain relief, but many people report having success with creams, lotions, and salves for all kinds of ailments.

Schilling JM, et al. (2021). Cannabidiol as a treatment for chronic pain: A survey of patients’ perspectives and attitudes.