Dragged Off to Hell: After Deadpool Out-Gambitted Vetis the first time, Mephisto dragged him to Hell for his incompetence. This was his final fate when Deadpool worked out a plan with Michael to cut a deal with Mephisto to swap Vetis' soul in exchange for breaking the contract he held everyone in. Evil Sorcerer: Washington gains some nasty magic stuff near the end of the resurrected presidents arc. If that's not enough to sell you at least on the concept, well, maybe the idea of an all-encompassing R-rated blast through a world where MCU characters who look a lot like the ones we know and love can say and do things their core MCU counterparts never could is enough to whet your whistle.

Dreadpool and Taskmaster face down for one final fight in the Man-Thing's swamp. When Dreadpool deliberately enables Taskmaster to mimic him, Taskmaster is horrified when he realizes the truth, enabling Man-Thing to kill him by touch.He starts with Reed Richards and the Fantastic Four, wiping them out entirely. Then he moves on to Uatu the Watcher, the supposedly non-interfering cosmic observer who watches and records the entire timeline of the Marvel Universe, who he also murders - but not before Uatu refuses to tell him on whose behalf he is observing the timeline. Evil Is Not a Toy: Michael probably should've realized using a magic book he got from a Deal with the Devil to resurrect dead presidents would end badly no matter what his intentions.

In Again, the Punisher finds a large, high-tech gun that Deadpool used to help kill the Guardians of the Galaxy, and keeps it so that he can use it on Deadpool himself. That's precisely what Deadpool wanted: as soon as the Punisher tries to fire it at him, the sabotaged gun vaporizes the Punisher instead.

Scalera's run

Agent X aka Marvel Legacy Deadpool #78-92: September 2002 to December 2003, issues #1-15. Cable was relaunched as Soldier X to more obviously tie-in to the X-Men, and Deadpool as a series similarly relaunched as Agent X, but the identity of the titular character is initially ambiguous as to whether it's actually Deadpool with amnesia, in disguise, or an Expy. The final issues post-cancellation reveals who Agent X is and reintroduce the real Deadpool in preparation for his next ongoing series, which pairs him with Cable. Straw Nihilist: Dreadpool's entire motive is that freedom from the horror of being a comic book character is enough to justify everything. Taken for Granite: Deadpool uses the mythological Medusa's head to do this to Thor, Loki, Hercules, Valkyrie, Hippolyta, and Ganesha in Again. They're later smashed to pieces to make sure they're gone. The crusade to oblierate existence has begun... And Deadpool is the progenitor of all things! — A Watcher Appearing in 1st story