Should be used with caution in patients with moderate to severe hepatic impairment and/or severe renal impairment as the clearance of nicotine or its metabolites may be decreased with the potential for increased adverse effects. If there is a clinically significant increase in cardiovascular or other effects attributable to nicotine, the nicotine gum dose should be reduced or discontinued. Nicotine is excreted in breast milk. Nicotine replacement therapy should therefore be avoided during breast-feeding. Should smoking withdrawal not be achieved, oral forms of nicotine replacement therapy gum may be considered as intermittent dose forms would minimize the amount of nicotine in breast milk and permit feeding when levels were at their lowest. People having problems with the joint of the jawbone and denture wearers may experience difficulty in chewing the gum. In this case, it is recommended that they use a different pharmaceutical form of nicotine replacement therapy.

Concomitant use of acidic beverages such as coffee or soda may decrease the buccal absorption of nicotine. Acidic beverages should be avoided for 15 minutes prior to chewing the gum. Swallowed nicotine may exacerbate symptoms in patients suffering from active oesophagitis, oral or pharyngeal inflammation, gastritis, or peptic ulcers and oral nicotine replacement therapy preparations should be used with caution in these conditions. Ulcerative stomatitis has been reported. Because Nicotinell gum contains sorbitol, xylitol and maltitol: Patients with rare hereditary conditions of fructose intolerance should not take this medicine. The following undesirable effects detailed in Table 1 are nicotine related adverse events for all oral dosage forms. Table 1 shows events which were identified from a double-blind, randomised, placebo-controlled lozenge clinical study involving 1818 patients. Adverse events reported in this study have been considered for inclusion, where the incidence in the 2 mg or 4 mg nicotine arm was higher than the corresponding placebo arm. Frequencies are calculated from safety data of the study.Treatment of overdose should be immediate as symptoms may develop rapidly (particularly in children). All nicotine intake should stop immediately. Emesis is usually spontaneous.

To help cut down or quit smoking you should also try to use a behavioural support programme to increase your chances of success. How does Nicotinell Gum help stop smoking?If you haven’t exercised for some time, take it slowly to begin with and increase the amount of time spent exercising over the course of a few weeks. Not only will exercising help you relax but it also helps to keep your weight under control, which some people find a problem when quitting. Think cash not ash

Whenever you feel the urge to smoke coming on, distract yourself by keeping active. Don’t feel sorry for yourself. Get up and do something. Do that job around the house or garden that you’ve been putting off or take up a hobby. Nicotinell Fruit Gum is a medicinal product used to help people stop smoking by providing relief of nicotine withdrawal symptoms. Your are more likely to quit smoking when using this product with help from your pharmacist, doctor, a trained counsellor or a support programme. It is indicated to aid smokers wishing to quit or reduce prior to quitting as well as to assist smokers who are unwilling or unable to smoke, and as a safer alternative to smoking for smokers and those around them.NRT products can be used to relieve withdrawal symptoms and reduce the cravings for nicotine that you get when you try to stop smoking, or when you are cutting down the number of cigarettes you smoke while trying to stop smoking. Just promise yourself “I won’t have a cigarette today” and take it one day at a time. You’ll be surprised how much that little thought helps. Patients with diabetes mellitus should be advised to monitor their blood sugar levels more closely than usual when nicotine replacement therapy is initiated as catecholamines released by nicotine can affect carbohydrate metabolism. Nicotinell Mint 2mg/4mg medicated chewing gum, Nicotinell Fruit 2mg/4mg medicated chewing gum (nicotine polacrilin). Nicotinell TTS 10, Nicotinell TTS 20, Nicotinell TTS 30 (nicotine). Nicotinell Mint 1mg/2mg Compressed Lozenges (nicotine bitartrate dihydrate).