Part 2 (PRA) of Commission Delegated Regulation (EU) No 1187/2014 of 2 October 2014 supplementing Regulation (EU) No 575/2013 of the European Parliament and of the Council as regards regulatory technical standards for determining the overall exposure to a client or a group of connected clients in respect of transactions with underlying assets

Rule 1.4 of Chapter 1 of the Large Exposures (CRR) Part corresponds to Article 2 of Part 2 (PRA) of Commission Delegated Regulation (EU) No 1187/2014 Regulatory Technical Standards on prudential requirements for central securities depositories (CSDs)Guidelines on criteria for the use of data inputs in the expected shortfall risk measure under the IMA

Regulatory Technical Standards on the margin periods for risk used for the treatment of clearing members' exposures to clients From the beginning this soliloquy has been regarded as special. It was frequently referred to by Shakespeare's contemporaries. It is the one speech from the play that Samuel Pepys chose to memorize. Its first line may well be the best-known single line in Shakespeare and indeed in world drama. Actors have sought to make it seem fresh (and to discourage auditors from reciting it with them). Mochalov, for example, ‘did not enter slowly, sunk in deep meditation, but came in almost running in a state of extreme nervous excitement, and then, stopping, cried: “To be or not to be” – and after several minutes of contemplation threw himself into an armchair, and uttered despairingly – “that is the question”’ (Speaight, Stage, p. 113). Guidelines to resolution authorities on the publication of their approach to implementing the bail-in tool

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Guidelines on common procedures and methodologies for the supervisory review and evaluation process (SREP)

PD-1–laIL-2 causes the proliferation of PD-1 +TIM3 +CD8 + effector T cells. A20 tumor-bearing mice ( n = 5/group) were treated with equal molar amounts of Erb–laIL-2 (20 μg) and anti–PD-1 (10 μg) (PD-1_Erb.laIL-2) or PD-1–laIL-2 (20 μg) on day 17. Three days later, CD3 + T cells from the tumor were sorted for single-cell RNA sequencing. ( A) Cd8b1 expression in each cluster. ( B) Percentages of each cluster in CD8 + T cell clusters. ( C– G) Gzma ( C), IFN-γ ( D), PD-1 ( E), TIM3 ( F), and Ki67 ( G) expression in each cluster. Cluster 5 was labeled. Part 2 (PRA) of Commission Delegated Regulation (EU) 2017/2295 of 4 September 2017 supplementing Regulation (EU) No 575/2013 of the European Parliament and of the Council with regard to regulatory technical standards for disclosure of encumbered and unencumbered assets. Part 2 (PRA) of Commission Delegated Regulation (EU) 2016/101 of 26 October 2015 supplementing Regulation (EU) No 575/2013 of the European Parliament and of the Council with regard to regulatory technical standards for prudent valuation under Article 105(14). Discussion paper on two delegated acts specifying further criteria for critical ICT third-party service providers (CTPPs) and determining oversight fees levied on such providers

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Regulatory Technical Standards on Individual Portfolio Management of loans offered by crowdfunding service providers Implementing Technical Standards on Supervisory Reporting amendments with regards to COREP securitisation Guidelines for common procedures and methodologies for the supervisory review and evaluation process (SREP) and supervisory stress testing Extension of the application of the Joint Committee Guidelines on complaints-handling to the new institutions under PSD2 and MCD